Indomethacin for recurrent cutaneous necrotizing eosinophilic vasculitis.

Recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) is a rare disease characterized by clinical features of pruritic purpuric papules and angioedema. Skin biopsies revealed the eosinophil-predominate necrotizing vasculitis affecting small dermal vessels. Systemic corticosteroid is a very effective treatment. There are many side effects associated with systemic corticosteroid therapy. The authors report a case of RCNEVsuccessfully treated with indomethacin. To the authors'knowledge, there has been no reported case of RCNEV treated with indomethacin.

Cutaneous metastases from visceral carcinoma in Siriraj Hospital: A retrospective review.

Cutaneous metastases occurred in 0.1% of all patients with cancer. The most common primary tumor was carcinoma of the breast (47.8%). They were recognized after the primary tumor in 56.5%. They were the first sign of cancer in 30.5%, especially in carcinoma of the lung. However, they were not uncommon as an early indicator of metastatic disease. They tended to appear in areas overlying the primary carcinoma. Only carcinoma of lung and cervix may disseminate to distant cutaneous sites. The prognosis depended on the type of primary carcinoma. Carcinoma of the breast with cutaneous metastases had a prolonged survival. Survival of patients with carcinoma of the lung averaged 2 months after the appearance of cutaneous metastases.

Poststeroid panniculitis in an adult.

Poststeroid panniculitis is a rare complication of corticosteroid therapy. All reported cases have occurred in children. In this communication, we describe a 41-year-old woman who presented to us with multiple subcutaneous nodules which appeared after reduction of the dose of oral prednisolone administered for systemic lupus erythematosus. Histopathological examination confirmed the diagnosis of poststeroid panniculitis. To our knowledge, this is the first case report in which poststeroid panniculitis occurs in an adult.

Treatment of pigmented basal cell carcinoma with carbon dioxide laser.

Seven patients with nine primary well-defined pigmented basal cell carcinomas (BCC), regardless of size, were successfully treated with carbon dioxide laser. There has been no evidence of recurrence in the 3 months to 2 years following surgery. This may be the result of the dermal pigment at the lesion shoulder that more clearly marks the tumor margin. However, if the tumor was located in the reticular dermis, healing occurred with an atrophic scar. Surgical excision is recommended in cases of deep BCCs located in the convex area in terms of cosmetic results. It is therefore suggested that, in addition to the BCC subtype, the depth of invasion should always be stated in the routine histopathological report in order to determine the most appropriate treatment.